Differin Gel is manufactured for the treatment of acne to clear and prevent acne from occurring again and again. It is a prescription medication and you need to consult the doctor prior using this gel.

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Promoted as a blackhead treatment, Differin gel is meant to clear acne and then prevent it from happening again. It uses 0.1% or 0.3% of their active ingredient, depending on which formulation you choose. It is supposed to be easier to tolerate for some patients, and it is largely sold through doctors. They even offer a free trial offer through the Differin website.

Differin Gel Ingredients

Active Ingredients: Adaptalene

Inactive Ingredients: carbomer 940, edetate disodium, methylparaben, poloxamer 124, propylene glycol, purified water, and sodium hydroxide Possible side effects of Differin include:

  1. Dryness,
  2. Itchiness, and
  3. Redness,
  4. Burning, and
  5. Peeling

They also note that your acne could actually get worse in the first few days. In addition, erythema or pruritus could occur with Differin gel. Animal studies have also shown birth defects in connection with Differin.

You Should Not Use Differin If You:

  • Suffer from allergies
  • Are over the age of 65
  • Are pregnant, and
  • Are taking certain medications or eating certain types of food such as alcohol or tobacco.

If you suffer from eczema or seborrheic dermatitis, you should also refrain from using this product. It should also not be combined with other acne treatments due to increased risk of skin irritation.

Differin is a prescription acne treatment for a reason. It comes with some relatively severe and studied side effects, and unlike benzyl peroxide, it is only used in extremely small concentrations, and cannot be found anywhere on the over the counter market.

Review Video

Differin Gel (Adapalene 0.1%)